When we lived in Texas, I discovered that soapy water was the most effective tool against fire ant mounds. I used one gallon (recycled milk jug) of hot water and added about a teaspoon of dish liquid. Pour over the mound and it will be gone within 24 hours!
For indoors, I just wipe up lines of ants with a soapy dish cloth, then find the source and - you guessed it - give them all a soapy bath!
Source: Homemade Ant Killer?
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