Roundup all the leaves you can. Poison oak usually requires another application, so leave the vine so you can find it again. The more leaves you spray, the better chance you have of getting all of it.
By llpensinger from Ocean City, MD
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I'd like to point out that, if you buy Roundup, you are supporting Monsanto, the company that introduced genetically modified foods into our food supply. A good deal of our corn and soy are now genetically modified because of Monsanto. Not everybody cares about that, but I thought I'd put it out there.
Also, Roundup is probably the most toxic herbacide available to residential consumers, so, be careful.
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